While. Avoid the indiscriminate use of this word for and, but, and although. Many writers use it frequently as a substitute for and or but, either from a mere desire to vary the connective or from doubt about which of the two connectives is more appropriate. In this use it is best replaced by a semicolon
The office and sales-rooms are on the ground floor, while the rest of the building is used for manufacturing | The office and sales-room are on the ground-floor; the rest of the building is used for manufacturing |
Its use as a virtual equivalent of although is allowable in sentences where this leads to no ambiguity or absurdity
While I admire his energy, I wish it were employed in a better cause.
This is entirely correct, as shown by the paraphrase
I admire his energy; at the same time, I wish it were employed in a better cause.
Compare:
While the temperature reaches 90 or 95 degrees in the daytime, the nights are often chilly.
The paraphrase shows why the use of while is incorrect:
The temperature reaches 90 or 95 degrees in the daytime; at the same time the nights are often chilly.
In general, the writer will do well to use while only with strict literalness, in the sense of “during the time that.”